Neprilysin-2 Is an Important β-Amyloid Degrading Enzyme

Proteases that degrade the amyloid-β peptide (Aβ) are important in protecting against Alzheimer's disease (AD), and understanding these proteases is critical to understanding AD pathology. Endopeptidases sensitive to inhibition by thiorphan and phosphoramidon are especially important, because t...

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Détails bibliographiques
Auteurs principaux: Hafez, Daniel, Huang, Jeffrey Y., Huynh, Alexis M., Valtierra, Stephanie, Rockenstein, Edward, Bruno, Angela M., Lu, Bao, DesGroseillers, Luc, Masliah, Eliezer, Marr, Robert A.
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2011
Sujets:
Regular Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069828/
https://ncbi.nlm.nih.gov/pubmed/21224067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.11.012
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