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Neprilysin-2 Is an Important β-Amyloid Degrading Enzyme

Proteases that degrade the amyloid-β peptide (Aβ) are important in protecting against Alzheimer's disease (AD), and understanding these proteases is critical to understanding AD pathology. Endopeptidases sensitive to inhibition by thiorphan and phosphoramidon are especially important, because t...

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Detalhes bibliográficos
Main Authors: Hafez, Daniel, Huang, Jeffrey Y., Huynh, Alexis M., Valtierra, Stephanie, Rockenstein, Edward, Bruno, Angela M., Lu, Bao, DesGroseillers, Luc, Masliah, Eliezer, Marr, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069828/
https://ncbi.nlm.nih.gov/pubmed/21224067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.11.012
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