Neprilysin-2 Is an Important β-Amyloid Degrading Enzyme

Proteases that degrade the amyloid-β peptide (Aβ) are important in protecting against Alzheimer's disease (AD), and understanding these proteases is critical to understanding AD pathology. Endopeptidases sensitive to inhibition by thiorphan and phosphoramidon are especially important, because t...

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Main Authors: Hafez, Daniel, Huang, Jeffrey Y., Huynh, Alexis M., Valtierra, Stephanie, Rockenstein, Edward, Bruno, Angela M., Lu, Bao, DesGroseillers, Luc, Masliah, Eliezer, Marr, Robert A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2011
Teme:
Regular Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069828/
https://ncbi.nlm.nih.gov/pubmed/21224067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.11.012
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