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Amyloid β-degrading cryptidases: insulin degrading enzyme, neprilysin, and presequence peptidase

The accumulation of aggregates of amyloidogenic peptides is associated with numerous human diseases. One well studied example is the association between deposition of amyloid β (Aβ) and Alzheimer’s disease. Insulin degrading enzyme and neprilysin are involved in the clearance of Aβ, and presequence...

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Detalhes bibliográficos
Main Authors: Malito, Enrico, Hulse, Raymond E., Tang, Wei-Jen
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756532/
https://ncbi.nlm.nih.gov/pubmed/18470479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-008-8112-4
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