Structure, Function, and Regulation of Insulin-Degrading Enzyme
The short half-life of insulin in the human body (4-6 min) prompted the search and discovery of insulin-degrading enzyme (IDE), a 110-kDa metalloprotease that can rapidly degrade insulin into inactive fragments. Genetic and biochemical evidence accumulated in the last sixty years has implicated IDE...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3656499/ https://ncbi.nlm.nih.gov/pubmed/19251053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0083-6729(08)00622-5 |
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