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Insulin-degrading Enzyme Modulates the Natriuretic Peptide-mediated Signaling Response

Natriuretic peptides (NPs) are cyclic vasoactive peptide hormones with high therapeutic potential. Three distinct NPs (ANP, BNP, and CNP) can selectively activate natriuretic peptide receptors, NPR-A and NPR-B, raising the cyclic GMP (cGMP) levels. Insulin-degrading enzyme (IDE) was found to rapidly...

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Detalles Bibliográficos
Main Authors: Ralat, Luis A., Guo, Qing, Ren, Min, Funke, Todd, Dickey, Deborah M., Potter, Lincoln R., Tang, Wei-Jen
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039328/
https://ncbi.nlm.nih.gov/pubmed/21098034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.173252
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