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Insulin-degrading Enzyme Modulates the Natriuretic Peptide-mediated Signaling Response
Natriuretic peptides (NPs) are cyclic vasoactive peptide hormones with high therapeutic potential. Three distinct NPs (ANP, BNP, and CNP) can selectively activate natriuretic peptide receptors, NPR-A and NPR-B, raising the cyclic GMP (cGMP) levels. Insulin-degrading enzyme (IDE) was found to rapidly...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3039328/ https://ncbi.nlm.nih.gov/pubmed/21098034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.173252 |
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