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HUMAN B-TYPE NATRIURETIC PEPTIDE IS NOT DEGRADED BY MEPRIN A

B-type natriuretic peptide (BNP) combats cardiac stress by reducing blood pressure and ventricular fibrosis. Human BNP is inactivated by unknown cell surface proteases. N-terminal cleavage of mouse BNP by the renal protease meprin A was reported to increase inactivating degradation by a second prote...

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Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Dickey, Deborah M., Potter, Lincoln R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495880/
https://ncbi.nlm.nih.gov/pubmed/20599787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.06.015
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