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Antibody Tracking Demonstrates Cell Type-Specific and Ligand-Independent Internalization of Guanylyl Cyclase A and Natriuretic Peptide Receptor C

Atrial natriuretic peptide (ANP) binds guanylyl cyclase-A (GC-A) and natriuretic peptide receptor-C (NPR-C). Internalization of GC-A and NPR-C is poorly understood, in part, because previous studies used (125)I-ANP binding to track these receptors, which are expressed in the same cell. Here, we eval...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Dickey, Deborah M., Flora, Darcy R., Potter, Lincoln R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5180442/
https://ncbi.nlm.nih.gov/pubmed/21498657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.070573
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