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HUMAN B-TYPE NATRIURETIC PEPTIDE IS NOT DEGRADED BY MEPRIN A
B-type natriuretic peptide (BNP) combats cardiac stress by reducing blood pressure and ventricular fibrosis. Human BNP is inactivated by unknown cell surface proteases. N-terminal cleavage of mouse BNP by the renal protease meprin A was reported to increase inactivating degradation by a second prote...
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| Veröffentlicht in: | Biochem Pharmacol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4495880/ https://ncbi.nlm.nih.gov/pubmed/20599787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.06.015 |
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