Potent Agonists of the Protease Activated Receptor 2 (PAR(2))

[Image: see text] Novel peptidomimetic pharmacophores to PAR(2) were designed based on the known activating peptide SLIGRL-NH(2). A set of 15 analogues was evaluated with a model cell line (16HBE14o-) that highly expresses PAR(2). Cells exposed to the PAR(2) activating peptide with N-terminal 2-furo...

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Autores principales: Boitano, Scott, Flynn, Andrea N., Schulz, Stephanie M., Hoffman, Justin, Price, Theodore J., Vagner, Josef
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069554/
https://ncbi.nlm.nih.gov/pubmed/21294569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm1013049
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