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RB deletion disrupts coordination between DNA replication licensing and mitotic entry in vivo
The integrity of the retinoblastoma tumor suppressor (RB) pathway is critical for restraining inappropriate proliferation and suppressing tumor development in a plethora of tissues. Here adenovirus-mediated RB deletion in the liver of adult mice led to DNA replication in the absence of productive mi...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The American Society for Cell Biology
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069018/ https://ncbi.nlm.nih.gov/pubmed/21289097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-11-0895 |
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