Single base discrimination for ribonuclease H-dependent antisense effects within intact human leukaemia cells.
We have previously demonstrated, in vitro, that phosphodiester and phosphorothioate antisense oligodeoxynucleotides could direct ribonuclease H to cleave non-target RNA sites and that chimeric methylphosphonodiester/phosphodiester analogue structures were substantially more specific. In this report...
Zapisane w:
| Wydane w: | Nucleic Acids Res |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
1995
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| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306791/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7731809/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.6.954 |
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