Novel cationic amphiphiles as delivery agents for antisense oligonucleotides.

There has been great interest recently in therapeutic use of nucleic acids including genes, ribozymes and antisense oligonucleotides. Despite recent improvements in delivering antisense oligonucleotides to cells in culture, nucleic acid-based therapy is still often limited by the poor penetration of...

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Detalhes bibliográficos
Main Authors: DeLong, R K, Yoo, H, Alahari, S K, Fisher, M, Short, S M, Kang, S H, Kole, R, Janout, V, Regan, S L, Juliano, R L
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC148567/
https://ncbi.nlm.nih.gov/pubmed/10454641
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