Novel cationic amphiphiles as delivery agents for antisense oligonucleotides.

There has been great interest recently in therapeutic use of nucleic acids including genes, ribozymes and antisense oligonucleotides. Despite recent improvements in delivering antisense oligonucleotides to cells in culture, nucleic acid-based therapy is still often limited by the poor penetration of...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	DeLong, R K, Yoo, H, Alahari, S K, Fisher, M, Short, S M, Kang, S H, Kole, R, Janout, V, Regan, S L, Juliano, R L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1999
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148567/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454641/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.16.3334
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