Single base discrimination for ribonuclease H-dependent antisense effects within intact human leukaemia cells.

We have previously demonstrated, in vitro, that phosphodiester and phosphorothioate antisense oligodeoxynucleotides could direct ribonuclease H to cleave non-target RNA sites and that chimeric methylphosphonodiester/phosphodiester analogue structures were substantially more specific. In this report...

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Detaylı Bibliyografya
Asıl Yazarlar: Giles, R V, Ruddell, C J, Spiller, D G, Green, J A, Tidd, D M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1995
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC306791/
https://ncbi.nlm.nih.gov/pubmed/7731809
Etiketler: Etiketle
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