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Autophagy Deficiency Promotes β-Lactam Production in Penicillium chrysogenum
We have investigated the significance of autophagy in the production of the β-lactam antibiotic penicillin (PEN) by the filamentous fungus Penicillium chrysogenum. In this fungus PEN production is compartmentalized in the cytosol and in peroxisomes. We demonstrate that under PEN-producing conditions...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3067201/ https://ncbi.nlm.nih.gov/pubmed/21169429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01531-10 |
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