Peroxisomes Are Required for Efficient Penicillin Biosynthesis in Penicillium chrysogenum

In the fungus Penicillium chrysogenum, penicillin (PEN) production is compartmentalized in the cytosol and in peroxisomes. Here we show that intact peroxisomes that contain the two final enzymes of PEN biosynthesis, acyl coenzyme A (CoA):6-amino penicillanic acid acyltransferase (AT) as well as the...

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Autors principals: Meijer, Wiebe H., Gidijala, Loknath, Fekken, Susan, Kiel, Jan A. K. W., van den Berg, Marco A., Lascaris, Romeo, Bovenberg, Roel A. L., van der Klei, Ida J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Mycology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935065/
https://ncbi.nlm.nih.gov/pubmed/20601503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02327-09
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