Peroxisomes Are Required for Efficient Penicillin Biosynthesis in Penicillium chrysogenum

In the fungus Penicillium chrysogenum, penicillin (PEN) production is compartmentalized in the cytosol and in peroxisomes. Here we show that intact peroxisomes that contain the two final enzymes of PEN biosynthesis, acyl coenzyme A (CoA):6-amino penicillanic acid acyltransferase (AT) as well as the...

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Main Authors: Meijer, Wiebe H., Gidijala, Loknath, Fekken, Susan, Kiel, Jan A. K. W., van den Berg, Marco A., Lascaris, Romeo, Bovenberg, Roel A. L., van der Klei, Ida J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Assuntos:
Mycology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935065/
https://ncbi.nlm.nih.gov/pubmed/20601503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02327-09
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