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Functional significance of the interaction with Ku in DNA double-strand break recognition of XLF
Ku heterodimer is essential for the repair of DNA double-strand breaks (DSBs) by non-homologous end-joining (NHEJ). Ku recruits XLF, also known as Cernunnos, to DSBs. Here we report domain analyses of Ku-XLF interaction. The heterodimeric domain of Ku was found to be sufficient for the recruitment o...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3066473/ https://ncbi.nlm.nih.gov/pubmed/21349273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2011.02.020 |
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