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FHIT gene therapy prevents tumor development in Fhit-deficient mice
The tumor suppressor gene FHIT spans a common fragile site and is highly susceptible to environmental carcinogens. FHIT inactivation and loss of expression is found in a large fraction of premaligant and malignant lesions. In this study, we were able to inhibit tumor development by oral gene transfe...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The National Academy of Sciences
2001
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC30656/ https://ncbi.nlm.nih.gov/pubmed/11248081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061020098 |
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