The tumor spectrum in FHIT-deficient mice

Mice carrying one inactivated Fhit allele (Fhit +/− mice) are highly susceptible to tumor induction by N-nitrosomethylbenzylamine, with 100% of Fhit +/− mice exhibiting tumors of the forestomach/squamocolumnar junction vs. 25% of Fhit +/+ controls. In the current study a single N-nitrosomethylbenzyl...

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Detalhes bibliográficos
Main Authors: Zanesi, Nicola, Fidanza, Vincenzo, Fong, Louise Y., Mancini, Rita, Druck, Teresa, Valtieri, Mauro, Rüdiger, Thomas, McCue, Peter A., Croce, Carlo M., Huebner, Kay
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC56947/
https://ncbi.nlm.nih.gov/pubmed/11517343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191345898
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