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Sequence of the FRA3B common fragile region: Implications for the mechanism of FHIT deletion

The hypothesis that chromosomal fragile sites may be “weak links” that result in hot spots for cancer-specific chromosome rearrangements was supported by the discovery that numerous cancer cell homozygous deletions and a familial translocation map within the FHIT gene, which encompasses the common f...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Inoue, Hiroshi, Ishii, Hideshi, Alder, Hansjuerg, Snyder, Eric, Druck, Teresa, Huebner, Kay, Croce, Carlo M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25062/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9405656/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.26.14584
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