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Sequence of the FRA3B common fragile region: Implications for the mechanism of FHIT deletion

The hypothesis that chromosomal fragile sites may be “weak links” that result in hot spots for cancer-specific chromosome rearrangements was supported by the discovery that numerous cancer cell homozygous deletions and a familial translocation map within the FHIT gene, which encompasses the common f...

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Autores principales: Inoue, Hiroshi, Ishii, Hideshi, Alder, Hansjuerg, Snyder, Eric, Druck, Teresa, Huebner, Kay, Croce, Carlo M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences of the USA 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC25062/
https://ncbi.nlm.nih.gov/pubmed/9405656
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