Muir–Torre-like syndrome in Fhit-deficient mice

To investigate the role of the Fhit gene in carcinogen induction of neoplasia, we have inactivated one Fhit allele in mouse embryonic stem cells and produced (129/SvJ × C57BL/6J) F(1) mice with a Fhit allele inactivated (+/−). Fhit +/+ and +/− mice were treated intragastrically with nitrosomethylben...

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Detalhes bibliográficos
Main Authors: Fong, Louise Y. Y., Fidanza, Vincenzo, Zanesi, Nicola, Lock, Leslie F., Siracusa, Linda D., Mancini, Rita, Siprashvili, Zurab, Ottey, Michelle, Martin, S. Eric, Druck, Teresa, McCue, Peter A., Croce, Carlo M., Huebner, Kay
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18303/
https://ncbi.nlm.nih.gov/pubmed/10758156
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