Muir–Torre-like syndrome in Fhit-deficient mice

To investigate the role of the Fhit gene in carcinogen induction of neoplasia, we have inactivated one Fhit allele in mouse embryonic stem cells and produced (129/SvJ × C57BL/6J) F(1) mice with a Fhit allele inactivated (+/−). Fhit +/+ and +/− mice were treated intragastrically with nitrosomethylben...

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Hlavní autoři: Fong, Louise Y. Y., Fidanza, Vincenzo, Zanesi, Nicola, Lock, Leslie F., Siracusa, Linda D., Mancini, Rita, Siprashvili, Zurab, Ottey, Michelle, Martin, S. Eric, Druck, Teresa, McCue, Peter A., Croce, Carlo M., Huebner, Kay
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2000
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC18303/
https://ncbi.nlm.nih.gov/pubmed/10758156
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