Muir–Torre-like syndrome in Fhit-deficient mice

To investigate the role of the Fhit gene in carcinogen induction of neoplasia, we have inactivated one Fhit allele in mouse embryonic stem cells and produced (129/SvJ × C57BL/6J) F(1) mice with a Fhit allele inactivated (+/−). Fhit +/+ and +/− mice were treated intragastrically with nitrosomethylben...

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Autori principali: Fong, Louise Y. Y., Fidanza, Vincenzo, Zanesi, Nicola, Lock, Leslie F., Siracusa, Linda D., Mancini, Rita, Siprashvili, Zurab, Ottey, Michelle, Martin, S. Eric, Druck, Teresa, McCue, Peter A., Croce, Carlo M., Huebner, Kay
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2000
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC18303/
https://ncbi.nlm.nih.gov/pubmed/10758156
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