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Dicationic phenyl-2, 2′-bichalcophenes and analogues as antiprotozoal agents

A series of phenyl-2, 2′-bichalcophene diamidines 1a-h were synthesized from the corresponding dinitriles either via a direct reaction with LiN(TMS)(2), followed by deprotection with ethanolic HCl or through the bis-O-acetoxyamidoxime followed by hydrogenation in acetic acid and EtOH over Pd-C. Thes...

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Detalhes bibliográficos
Main Authors: Ismail, Mohamed A., El Bialy, Serry A., Brun, Reto, Wenzler, Tanja, Nanjunda, Rupesh, Wilson, W. David, Boykin, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064985/
https://ncbi.nlm.nih.gov/pubmed/21194955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.11.047
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