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Indole and Benzimidazole Bichalcophenes: Synthesis, DNA Binding and Antiparasitic Activity

A novel series of indole and benzimidazole bichalcophene diamidine derivatives were prepared to study their antimicrobial activity against the tropical parasites causing African sleeping sickness and malaria. The dicyanoindoles needed to synthesize the target diamidines were obtained through Stille...

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Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: Farahat, Abdelbasset A., Ismail, Mohamed A., Kumar, Arvind, Wenzler, Tanja, Brun, Reto, Paul, Ananya, Wilson, W. David, Boykin, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: Editions Scientifiques Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744864/
https://ncbi.nlm.nih.gov/pubmed/29126729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2017.10.056
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