Indole and Benzimidazole Bichalcophenes: Synthesis, DNA Binding and Antiparasitic Activity

A novel series of indole and benzimidazole bichalcophene diamidine derivatives were prepared to study their antimicrobial activity against the tropical parasites causing African sleeping sickness and malaria. The dicyanoindoles needed to synthesize the target diamidines were obtained through Stille...

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Bibliographic Details
Published in:Eur J Med Chem
Main Authors: Farahat, Abdelbasset A., Ismail, Mohamed A., Kumar, Arvind, Wenzler, Tanja, Brun, Reto, Paul, Ananya, Wilson, W. David, Boykin, David W.
Format: Artigo
Language:Inglês
Published: Editions Scientifiques Elsevier 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744864/
https://ncbi.nlm.nih.gov/pubmed/29126729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2017.10.056
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