Indole and Benzimidazole Bichalcophenes: Synthesis, DNA Binding and Antiparasitic Activity

A novel series of indole and benzimidazole bichalcophene diamidine derivatives were prepared to study their antimicrobial activity against the tropical parasites causing African sleeping sickness and malaria. The dicyanoindoles needed to synthesize the target diamidines were obtained through Stille...

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Gepubliceerd in:Eur J Med Chem
Hoofdauteurs: Farahat, Abdelbasset A., Ismail, Mohamed A., Kumar, Arvind, Wenzler, Tanja, Brun, Reto, Paul, Ananya, Wilson, W. David, Boykin, David W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Editions Scientifiques Elsevier 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744864/
https://ncbi.nlm.nih.gov/pubmed/29126729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2017.10.056
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