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Differential effects of nitric oxide on blood–brain barrier integrity and cerebral blood flow in intracerebral C6 gliomas
Nitric oxide (NO) signaling in tumors and endothelial cells regulates vascular permeability and blood flow and therefore influences tumor uptake and response to therapeutic compounds. As delivery and efficacy of chemotherapy is impaired in CNS neoplasms due to a partially intact blood–brain barrier...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064621/ https://ncbi.nlm.nih.gov/pubmed/21041233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq161 |
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