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Marizomib activity as a single agent in malignant gliomas: ability to cross the blood-brain barrier
BACKGROUND: The proteasome plays a vital role in the physiology of glioblastoma (GBM), and proteasome inhibition can be used as a strategy for treating GBM. Marizomib is a second-generation, irreversible proteasome inhibitor with a more lipophilic structure that suggests the potential for penetratin...
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| Publicado en: | Neuro Oncol |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4864261/ https://ncbi.nlm.nih.gov/pubmed/26681765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov299 |
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