P53 impairs endothelial function by transcriptionally repressing Kruppel-like factor 2

OBJECTIVE: Endothelial Kruppel-like factor 2 (KLF2) mediates endothelium-dependent vascular homeostasis by differentially regulating endothelial genes, leading to an anti-inflammatory and anti-thrombotic endothelial surface with normal vasodilatory function. In contrast, the tumor suppressor p53 lea...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kumar, Ajay, Kim, Cuk-Seong, Hoffman, Timothy A., Naqvi, Asma, DeRicco, Jeremy, Jung, Saet-Byel, Lin, Zhiyong, Jain, Mukesh K., Irani, Kaikobad
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064482/
https://ncbi.nlm.nih.gov/pubmed/20947822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.215061
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