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SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase
Reduced caloric intake decreases arterial blood pressure in healthy individuals and improves endothelium-dependent vasodilation in obese and overweight individuals. The SIRT1 protein deacetylase mediates many of the effects of calorie restriction (CR) on organismal lifespan and metabolic pathways. H...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1976244/ https://ncbi.nlm.nih.gov/pubmed/17785417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704329104 |
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