Hallmarks of Molecular Action of Microtubule Stabilizing Agents: EFFECTS OF EPOTHILONE B, IXABEPILONE, PELORUSIDE A, AND LAULIMALIDE ON MICROTUBULE CONFORMATION

Microtubule stabilizing agents (MSAs) comprise a class of drugs that bind to microtubule (MT) polymers and stabilize them against disassembly. Several of these agents are currently in clinical use as anticancer drugs, whereas others are in various stages of development. Nonetheless, there is insuffi...

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Bibliografiska uppgifter
Huvudupphovsmän: Khrapunovich-Baine, Marina, Menon, Vilas, Yang, Chia-Ping Huang, Northcote, Peter T., Miller, John H., Angeletti, Ruth Hogue, Fiser, Andras, Horwitz, Susan Band, Xiao, Hui
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2011
Ämnen:
Protein Structure and Folding
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064228/
https://ncbi.nlm.nih.gov/pubmed/21245138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.162214
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