Hallmarks of Molecular Action of Microtubule Stabilizing Agents: EFFECTS OF EPOTHILONE B, IXABEPILONE, PELORUSIDE A, AND LAULIMALIDE ON MICROTUBULE CONFORMATION

Microtubule stabilizing agents (MSAs) comprise a class of drugs that bind to microtubule (MT) polymers and stabilize them against disassembly. Several of these agents are currently in clinical use as anticancer drugs, whereas others are in various stages of development. Nonetheless, there is insuffi...

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Bibliografiske detaljer
Main Authors: Khrapunovich-Baine, Marina, Menon, Vilas, Yang, Chia-Ping Huang, Northcote, Peter T., Miller, John H., Angeletti, Ruth Hogue, Fiser, Andras, Horwitz, Susan Band, Xiao, Hui
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064228/
https://ncbi.nlm.nih.gov/pubmed/21245138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.162214
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