Hallmarks of Molecular Action of Microtubule Stabilizing Agents: EFFECTS OF EPOTHILONE B, IXABEPILONE, PELORUSIDE A, AND LAULIMALIDE ON MICROTUBULE CONFORMATION

Microtubule stabilizing agents (MSAs) comprise a class of drugs that bind to microtubule (MT) polymers and stabilize them against disassembly. Several of these agents are currently in clinical use as anticancer drugs, whereas others are in various stages of development. Nonetheless, there is insuffi...

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Bibliografski detalji
Glavni autori: Khrapunovich-Baine, Marina, Menon, Vilas, Yang, Chia-Ping Huang, Northcote, Peter T., Miller, John H., Angeletti, Ruth Hogue, Fiser, Andras, Horwitz, Susan Band, Xiao, Hui
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Protein Structure and Folding
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064228/
https://ncbi.nlm.nih.gov/pubmed/21245138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.162214
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