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Lef1ΔN Binds β-Catenin and Increases Osteoblast Activity and Trabecular Bone Mass

Lymphoid enhancer-binding factor (Lef) 1 is a high mobility group protein best known as a Wnt-responsive transcription factor that associates with β-catenin. Lef1ΔN is a short isoform of Lef1 that lacks the first 113 amino acids and a well characterized high affinity β-catenin binding domain present...

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Hlavní autoři: Hoeppner, Luke H., Secreto, Frank J., Razidlo, David F., Whitney, Tiffany J., Westendorf, Jennifer J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064150/
https://ncbi.nlm.nih.gov/pubmed/21270130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.165100
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