PPARδ-mediated mitochondrial rewiring of osteoblasts determines bone mass

Bone turnover, which is determined by osteoclast-mediated bone resorption and osteoblast-mediated bone formation, represents a highly energy consuming process. The metabolic requirements of osteoblast differentiation and mineralization, both essential for regular bone formation, however, remain inco...

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Publicat a:Sci Rep
Autors principals: Müller, Dorothea I. H., Stoll, Cornelia, Palumbo-Zerr, Katrin, Böhm, Christina, Krishnacoumar, Brenda, Ipseiz, Natacha, Taubmann, Jule, Zimmermann, Max, Böttcher, Martin, Mougiakakos, Dimitrios, Tuckermann, Jan, Djouad, Farida, Schett, Georg, Scholtysek, Carina, Krönke, Gerhard
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242479/
https://ncbi.nlm.nih.gov/pubmed/32439961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65305-5
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