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Wnt Signaling as a Therapeutic Target for Bone Diseases

BACKGROUND: There is a need to develop new bone anabolic agents because current bone regeneration regimens have limitations. The Wingless-type MMTV integration site (Wnt) pathway has emerged as a crucial regulator of bone formation and regeneration. OBJECTIVE: Toreview the molecular basis for Wnt pa...

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Detalhes bibliográficos
Main Authors: Hoeppner, Luke H., Secreto, Frank J., Westendorf, Jennifer J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023986/
https://ncbi.nlm.nih.gov/pubmed/19335070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728220902841961
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