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Runx2 and Bone Morphogenic Protein 2 Regulate the Expression of an Alternative Lef1 Transcript During Osteoblast Maturation

Lymphoid Enhancer Binding Factor (Lef) 1 is a transcriptional effector of the Wnt/Lrp5/β-catenin signaling cascade, which regulates osteoblast differentiation, bone density and skeletal strength. In this study, we describe the expression and function of an alternative Lef1 isoform in osseous cells....

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Bibliografski detalji
Glavni autori: Hoeppner, Luke H., Secreto, Frank, Jensen, Eric D., Li, Xiaodong, Kahler, Rachel A., Westendorf, Jennifer J.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874810/
https://ncbi.nlm.nih.gov/pubmed/19650108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21879
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