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Runx2 and Bone Morphogenic Protein 2 Regulate the Expression of an Alternative Lef1 Transcript During Osteoblast Maturation
Lymphoid Enhancer Binding Factor (Lef) 1 is a transcriptional effector of the Wnt/Lrp5/β-catenin signaling cascade, which regulates osteoblast differentiation, bone density and skeletal strength. In this study, we describe the expression and function of an alternative Lef1 isoform in osseous cells....
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3874810/ https://ncbi.nlm.nih.gov/pubmed/19650108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21879 |
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