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Collagen 11a1 is Indirectly Activated by Lymphocyte Enhancer-binding Factor 1 (Lef1) and Negatively Regulates Osteoblast Maturation

Alpha 1 (XI) collagen (Col11a1) is essential for normal skeletal development. Mutations in Col11a1 cause Marshall and Stickler syndromes, both of which are characterized by craniofacial abnormalities, nearsightedness and hearing deficiencies. Despite its link to human diseases, few studies have desc...

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Detalhes bibliográficos
Main Authors: Kahler, Rachel A., Yingst, Sorcha M.C., Hoeppner, Luke H., Jensen, Eric D., Krawczak, David, Oxford, Julia T., Westendorf, Jennifer J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431459/
https://ncbi.nlm.nih.gov/pubmed/18280717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2008.01.002
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