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Histone Deacetylase 7 Associates With Runx2 and Represses Its Activity During Osteoblast Maturation in a Deacetylation-Independent Manner
HDAC7 associates with Runx2 and represses Runx2 transcriptional activity in a deacetylase-independent manner. HDAC7 suppression accelerates osteoblast maturation. Thus, HDAC7 is a novel Runx2 co-repressor that regulates osteoblast differentiation. INTRODUCTION: Runx2 is a key regulator of gene expre...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Amer Soc Bone & Mineral Res.
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669158/ https://ncbi.nlm.nih.gov/pubmed/17997710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.071104 |
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