Histone Deacetylase Inhibition Promotes Osteoblast Maturation by Altering the Histone H4 Epigenome and Reduces Akt Phosphorylation

Bone has remarkable regenerative capacity, but this ability diminishes during aging. Histone deacetylase inhibitors (HDIs) promote terminal osteoblast differentiation and extracellular matrix production in culture. The epigenetic events altered by HDIs in osteoblasts may hold clues for the developme...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Dudakovic, Amel, Evans, Jared M., Li, Ying, Middha, Sumit, McGee-Lawrence, Meghan E., van Wijnen, Andre J., Westendorf, Jennifer J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Gene Regulation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789974/
https://ncbi.nlm.nih.gov/pubmed/23940046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.489732
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak