Histone deacetylase 3 is required for maintenance of bone mass during aging

Histone deacetylase 3 (Hdac3) is a nuclear enzyme that removes acetyl groups from lysine residues in histones and other proteins to epigenetically regulate gene expression. Hdac3 interacts with bone-related transcription factors and co-factors such as Runx2 and Zfp521, and thus is poised to play a k...

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Huvudupphovsmän: McGee-Lawrence, Meghan E., Bradley, Elizabeth W., Dudakovic, Amel, Carlson, Samuel W., Ryan, Zachary C., Kumar, Rajiv, Dadsetan, Mahrokh, Yaszemski, Michael J., Chen, Qingshan, An, Kai-Nan, Westendorf, Jennifer J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513670/
https://ncbi.nlm.nih.gov/pubmed/23085085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2012.10.015
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