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Histone Deacetylases in Bone Development and Skeletal Disorders
Histone deacetylases (Hdacs) are conserved enzymes that remove acetyl groups from lysine side chains in histones and other proteins. Eleven of the 18 Hdacs encoded by the human and mouse genomes depend on Zn(2+) for enzymatic activity, while the other 7, the sirtuins (Sirts), require NAD2(+). Collec...
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| Publicado no: | Physiol Rev |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4600951/ https://ncbi.nlm.nih.gov/pubmed/26378079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physrev.00004.2015 |
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