Histone Deacetylases in Bone Development and Skeletal Disorders

Histone deacetylases (Hdacs) are conserved enzymes that remove acetyl groups from lysine side chains in histones and other proteins. Eleven of the 18 Hdacs encoded by the human and mouse genomes depend on Zn(2+) for enzymatic activity, while the other 7, the sirtuins (Sirts), require NAD2(+). Collec...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Physiol Rev
Main Authors: Bradley, Elizabeth W., Carpio, Lomeli R., van Wijnen, Andre J., McGee-Lawrence, Meghan E., Westendorf, Jennifer J.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2015
Teme:
Reviews
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600951/
https://ncbi.nlm.nih.gov/pubmed/26378079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physrev.00004.2015
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki