Histone deacetylase inhibition destabilizes the multi-potent state of uncommitted adipose-derived mesenchymal stromal cells

Human adipose-derived mesenchymal stromal cells (AMSCs) grown in platelet lysate are promising agents for therapeutic tissue regeneration. Here, we investigated whether manipulation of epigenetic events by the clinically relevant histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) a...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Dudakovic, Amel, Camilleri, Emily T., Lewallen, Eric A., McGee-Lawrence, Meghan E., Riester, Scott M., Kakar, Sanjeev, Montecino, Martin, Stein, Gary S., Ryoo, Hyun-Mo, Dietz, Allan B., Westendorf, Jennifer J., van Wijnen, Andre J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225068/
https://ncbi.nlm.nih.gov/pubmed/24912092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24680
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