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Histone Deacetylase 10 Relieves Repression on the Melanogenic Program by Maintaining the Deacetylation Status of Repressors

HDAC10 belongs to the class II histone deacetylase family; however, its functions remain enigmatic. We report here that the HDAC10 protein complex contained deacetylated chaperone protein hsc70, and HDAC10 relieved repression of melanogenesis by decreasing the repressional activity of two transcript...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lai, I-Lu, Lin, Tung-Ping, Yao, Ya-Li, Lin, Ching-Yi, Hsieh, Mei-Ju, Yang, Wen-Ming
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844168/
https://ncbi.nlm.nih.gov/pubmed/20032463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.061861
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