Histone Deacetylase 10 Relieves Repression on the Melanogenic Program by Maintaining the Deacetylation Status of Repressors

HDAC10 belongs to the class II histone deacetylase family; however, its functions remain enigmatic. We report here that the HDAC10 protein complex contained deacetylated chaperone protein hsc70, and HDAC10 relieved repression of melanogenesis by decreasing the repressional activity of two transcript...

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Bibliografische gegevens
Hoofdauteurs: Lai, I-Lu, Lin, Tung-Ping, Yao, Ya-Li, Lin, Ching-Yi, Hsieh, Mei-Ju, Yang, Wen-Ming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2010
Onderwerpen:
Gene Regulation
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844168/
https://ncbi.nlm.nih.gov/pubmed/20032463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.061861
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