Histone Deacetylase 10 Relieves Repression on the Melanogenic Program by Maintaining the Deacetylation Status of Repressors

HDAC10 belongs to the class II histone deacetylase family; however, its functions remain enigmatic. We report here that the HDAC10 protein complex contained deacetylated chaperone protein hsc70, and HDAC10 relieved repression of melanogenesis by decreasing the repressional activity of two transcript...

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Bibliographic Details
Main Authors: Lai, I-Lu, Lin, Tung-Ping, Yao, Ya-Li, Lin, Ching-Yi, Hsieh, Mei-Ju, Yang, Wen-Ming
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Gene Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844168/
https://ncbi.nlm.nih.gov/pubmed/20032463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.061861
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