Histone Deacetylase 10 Relieves Repression on the Melanogenic Program by Maintaining the Deacetylation Status of Repressors

HDAC10 belongs to the class II histone deacetylase family; however, its functions remain enigmatic. We report here that the HDAC10 protein complex contained deacetylated chaperone protein hsc70, and HDAC10 relieved repression of melanogenesis by decreasing the repressional activity of two transcript...

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Autores principales: Lai, I-Lu, Lin, Tung-Ping, Yao, Ya-Li, Lin, Ching-Yi, Hsieh, Mei-Ju, Yang, Wen-Ming
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Gene Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844168/
https://ncbi.nlm.nih.gov/pubmed/20032463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.061861
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