Transcriptional Repression of Histone Deacetylase 3 by the Histone Demethylase KDM2A Is Coupled to Tumorigenicity of Lung Cancer Cells

Dysregulated expression of histone methyltransferases and demethylases is an emerging epigenetic mechanism underlying cancer development and metastasis. We recently showed that the histone H3 lysine 36 (H3K36) demethylase KDM2A (also called FBXL11 and JHDM1A) is necessary for tumorigenic and metasta...

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Bibliografiske detaljer
Main Authors: Dhar, Shilpa S., Alam, Hunain, Li, Na, Wagner, Klaus W., Chung, Jimyung, Ahn, Yeo Won, Lee, Min Gyu
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Gene Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953262/
https://ncbi.nlm.nih.gov/pubmed/24482232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.521625
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