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Transcriptional Repression of Histone Deacetylase 3 by the Histone Demethylase KDM2A Is Coupled to Tumorigenicity of Lung Cancer Cells

Dysregulated expression of histone methyltransferases and demethylases is an emerging epigenetic mechanism underlying cancer development and metastasis. We recently showed that the histone H3 lysine 36 (H3K36) demethylase KDM2A (also called FBXL11 and JHDM1A) is necessary for tumorigenic and metasta...

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Bibliografski detalji
Glavni autori: Dhar, Shilpa S., Alam, Hunain, Li, Na, Wagner, Klaus W., Chung, Jimyung, Ahn, Yeo Won, Lee, Min Gyu
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953262/
https://ncbi.nlm.nih.gov/pubmed/24482232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.521625
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