Retinoblastoma Protein Transcriptional Repression through Histone Deacetylation of a Single Nucleosome

The retinoblastoma protein, pRb, controls transcription through recruitment of histone deacetylase to particular E2F-responsive genes. We determined the acetylation level of individual nucleosomes present in the cyclin E promoter of RB(+/+) and RB(−/−) mouse embryo fibroblasts. We also determined th...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Morrison, Ashby J., Sardet, Claude, Herrera, Rafael E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2002
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133558/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11784861/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.3.856-865.2002
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