Retinoblastoma Protein Transcriptional Repression through Histone Deacetylation of a Single Nucleosome

The retinoblastoma protein, pRb, controls transcription through recruitment of histone deacetylase to particular E2F-responsive genes. We determined the acetylation level of individual nucleosomes present in the cyclin E promoter of RB(+/+) and RB(−/−) mouse embryo fibroblasts. We also determined th...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Morrison, Ashby J., Sardet, Claude, Herrera, Rafael E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Transcriptional Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC133558/
https://ncbi.nlm.nih.gov/pubmed/11784861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.3.856-865.2002
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky