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The histone deacetylase HDAC3 targets RbAp48 to the retinoblastoma protein
The product of the retinoblastoma susceptibility gene, the Rb protein, functions partly through transcriptional repression of E2F-regulated genes. Repression by Rb is mediated, at least in part, by a histone deacetylase complex, whose enzymatic activity relies on HDAC1, HDAC2 or HDAC3. Recently, we...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Oxford University Press
2001
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC55834/ https://ncbi.nlm.nih.gov/pubmed/11470869 |
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