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The histone deacetylase HDAC3 targets RbAp48 to the retinoblastoma protein

The product of the retinoblastoma susceptibility gene, the Rb protein, functions partly through transcriptional repression of E2F-regulated genes. Repression by Rb is mediated, at least in part, by a histone deacetylase complex, whose enzymatic activity relies on HDAC1, HDAC2 or HDAC3. Recently, we...

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Autores principales: Nicolas, Estelle, Ait-Si-Ali, Slimane, Trouche, Didier
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC55834/
https://ncbi.nlm.nih.gov/pubmed/11470869
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